The Top 8 Bioinformatics Cancer Genomics Mutational Signatures Open Source Projects

Open source projects categorized as Bioinformatics Cancer Genomics Mutational Signatures

Categories > Data Processing > Bioinformatics

Categories > Science > Cancer Genomics

Categories > Mutational Signatures

SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.

dependent packages 3total releases 50most recent commit 5 months ago

Sigprofilermatrixgenerator ⭐ 91

SigProfilerMatrixGenerator creates mutational matrices for all types of somatic mutations. It allows downsizing the generated mutations only to parts for the genome (e.g., exome or a custom BED file). The tool seamlessly integrates with other SigProfiler tools.

dependent packages 10total releases 102most recent commit 3 months ago

pypi SigProfilerMatrixGenerator} Downloads

Palimpsest ⭐ 56

An R package for studying mutational signatures and structural variant signatures along clonal evolution in cancer.

most recent commit 3 years ago

Sigprofilersimulator ⭐ 18

SigProfilerSimulator allows realistic simulations of mutational patterns and mutational signatures in cancer genomes. The tool can be used to simulate signatures of single point mutations, double point mutations, and insertion/deletions. Further, the tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.

most recent commit 7 months ago

Sigprofilermatrixgeneratorr ⭐ 17

R wrapper for utilizing the SigProfilerMatrixGenerator framework

most recent commit a year ago

Sigprofilertopography ⭐ 13

SigProfilerTopography allows evaluating the effect of chromatin organization, histone modifications, transcription factor binding, DNA replication, and DNA transcription on the activities of different mutational processes. SigProfilerTopography elucidates the unique topographical characteristics of mutational signatures.

dependent packages 1total releases 250most recent commit 3 months ago

Sigprofilerextractorr ⭐ 11

An R wrapper for SigProfilerExtractor that allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.

most recent commit a year ago

Sigprofilerclusters ⭐ 8

Tool for analyzing the inter-mutational distances between SNV-SNV and INDEL-INDEL mutations. Tool separates mutations into clustered and non-clustered groups on a sample-dependent basis.

most recent commit 5 months ago

The 3 Most Depended On Bioinformatics Cancer Genomics Mutational Signatures Open Source Projects

Sigprofilermatrixgenerator ⭐ 91

dependent packages 10total releases 102latest release October 02, 2023most recent commit 3 months ago

Sigprofilerextractor ⭐ 132

dependent packages 3total releases 50latest release November 21, 2023most recent commit 5 months ago

Sigprofilertopography ⭐ 13

dependent packages 1total releases 250latest release December 03, 2023most recent commit 3 months ago

The 3 Latest Releases In Bioinformatics Cancer Genomics Mutational Signatures Open Source Projects

Sigprofilertopography ⭐ 13

dependent packages 1total releases 250latest release December 03, 2023most recent commit 3 months ago

Sigprofilerextractor ⭐ 132

dependent packages 3total releases 50latest release November 21, 2023most recent commit 5 months ago

Sigprofilermatrixgenerator ⭐ 91

dependent packages 10total releases 102latest release October 02, 2023most recent commit 3 months ago

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