Sigprofilersimulator
SigProfilerSimulator allows realistic simulations of mutational patterns and mutational signatures in cancer genomes. The tool can be used to simulate signatures of single point mutations, double point mutations, and insertion/deletions. Further, the tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.
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|---|---|---|---|---|---|---|---|---|---|---|
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| Sigprofilerextractor | 132 |  | 3 | 5 months ago | 50 | November 21, 2023 | 1 | bsd-2-clause | Python | |
| SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting. | ||||||||||
| Sigprofilermatrixgenerator | 91 |  | 1 | 10 | 3 months ago | 102 | October 02, 2023 | 5 | bsd-2-clause | Python |
| SigProfilerMatrixGenerator creates mutational matrices for all types of somatic mutations. It allows downsizing the generated mutations only to parts for the genome (e.g., exome or a custom BED file). The tool seamlessly integrates with other SigProfiler tools. | ||||||||||
| Agfusion | 46 |  | 1 | a year ago | 38 | February 10, 2023 | 4 | mit | Python | |
| Python package to annotate and visualize gene fusions. | ||||||||||
| Genome Nexus | 38 | 4 months ago | 194 | mit | Java | |||||
| Backend server for Genome Nexus | ||||||||||
| Sigprofilersimulator | 18 | 7 months ago | bsd-2-clause | Python | ||||||
| SigProfilerSimulator allows realistic simulations of mutational patterns and mutational signatures in cancer genomes. The tool can be used to simulate signatures of single point mutations, double point mutations, and insertion/deletions. Further, the tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting. | ||||||||||
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Python
Assembly
Bioinformatics
Genome
Cancer Genomics