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A PyTorch Basecaller for Oxford Nanopore Reads

Megalodon ⭐ 172

Megalodon is a research command line tool to extract high accuracy modified base and sequence variant calls from raw nanopore reads by anchoring the information rich basecalling neural network output to a reference genome/transriptome.

Methylation/modified base calling separated from basecalling.

Research release basecalling models and configurations

Pyguppyclient ⭐ 25

Python client library for Guppy

Modphred ⭐ 12

modPhred is a pipeline for detection of DNA/RNA modifications from raw ONT data

Nanopore direct RNA basecaller

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