Clustergrammer is a web-based tool for visualizing high-dimensional data (e.g. a matrix) as an interactive and shareable hierarchically clustered heatmap. Clustergrammer's front end (Clustergrammer-JS) is built using D3.js and its back-end (Clustergrammer-PY) is built using Python. Clustergrammer produces highly interactive visualizations that enable intuitive exploration of high-dimensional data and has several biology-specific features (e.g. enrichment analysis, see Biology-Specific Features) to facilitate the exploration of gene-level biological data. Click the screenshot below to view an interactive tutorial:

Clustergrammer's interacive features include:

• Zooming and Panning
• Row and Column Reordering
• Interactive Dendrogram
• Interactive Dimensionality Reduction
• Interactive Categories
• Cropping
• Row Searching
• Biology-Specific Features

Clustergrammer can be used in three main ways (this repo contains the source code for Clustergrammer-JS):

• Clustergrammer Web App (http://amp.pharm.mssm.edu/clustergrammer/)
• Clustergrammer Jupyter Widget
• Clustergrammer-JS and Clustergrammer-PY libraries

For information about building a webpage or app using Clustergrammer see: Web-Development with Clustergrammer

Clustergrammer is being re-built using the WebGL library regl. The new in-development front-end is Clustergrammer-GL and the new in-development Jupyter widget is Clustergrammer2. The above notebook shows how Clustergrammer2 can be used to load a small dataset and visualize a large random DataFrame. By running the notebook on MyBinder using Jupyter Lab it can also be used to visualize a user uploaded dataset. Please see the video tutorial above for more information.

For additional examples and tutorials please see:

• Case Studies and Tutorials
• Clustergrammer2-Notebooks GitHub repository

Clustergrammer was recently presented at JupyterCon 2018 (see slides).

Pleae see Clustergramer's documentation for detailed information or select a specific topic below:

• Getting Started
• Interacting with the Visualization
• Web-Development with Clustergrammer (example pages)
• Clustergrammer Web App and Clustergrammer Jupyter Widget
• Matrix Formats and Input/Output
• Core libraries: Clustergrammer-JS and Clustergrammer-PY
• App Integration Examples
• Case Studies and Examples
• Biology-Specific Features
• Developing Clustergrammer

Please consider supporting Clustergrammer by citing our publication:

Fernandez, N. F. et al. Clustergrammer, a web-based heatmap visualization and analysis tool for high-dimensional biological data. Sci. Data 4:170151 doi: 10.1038/sdata.2017.151 (2017).

Clustergrammer was developed by the Ma'ayan lab at the Icahn School of Medicine at Mount Sinai for the BD2K-LINCS DCIC and the KMC-IDG. Clustergrammer's license and third-party licenses are in the LICENSES directory and more information can be found at Clustergrammer License.

Please contact us for support, licensing questions, comments, and suggestions.