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The Top 6 Bioinformatics Cancer Genomics Somatic Variants Mutational Signatures Open Source Projects

Open source projects categorized as Bioinformatics Cancer Genomics Somatic Variants Mutational Signatures
Categories > Data Processing > Bioinformatics
Categories > Science > Cancer Genomics
Categories > Mutational Signatures
Categories > Somatic Variants
Sigprofilerextractor ⭐ 132
SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.
dependent packages 3total releases 50most recent commit 5 months agopypi SigProfilerExtractor} Downloads
Sigprofilermatrixgenerator ⭐ 91
SigProfilerMatrixGenerator creates mutational matrices for all types of somatic mutations. It allows downsizing the generated mutations only to parts for the genome (e.g., exome or a custom BED file). The tool seamlessly integrates with other SigProfiler tools.
dependent packages 10total releases 102most recent commit 3 months agopypi SigProfilerMatrixGenerator} Downloads
Sigprofilersimulator ⭐ 18
SigProfilerSimulator allows realistic simulations of mutational patterns and mutational signatures in cancer genomes. The tool can be used to simulate signatures of single point mutations, double point mutations, and insertion/deletions. Further, the tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.
most recent commit 7 months ago
Sigprofilermatrixgeneratorr ⭐ 17
R wrapper for utilizing the SigProfilerMatrixGenerator framework
most recent commit a year ago
Sigprofilertopography ⭐ 13
SigProfilerTopography allows evaluating the effect of chromatin organization, histone modifications, transcription factor binding, DNA replication, and DNA transcription on the activities of different mutational processes. SigProfilerTopography elucidates the unique topographical characteristics of mutational signatures.
dependent packages 1total releases 250most recent commit 3 months agopypi SigProfilerTopography} Downloads
Sigprofilerextractorr ⭐ 11
An R wrapper for SigProfilerExtractor that allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.
most recent commit a year ago
The 3 Most Depended On Bioinformatics Cancer Genomics Somatic Variants Mutational Signatures Open Source Projects
The 3 Latest Releases In Bioinformatics Cancer Genomics Somatic Variants Mutational Signatures Open Source Projects
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